Aeromonas hydrophila utilizes TLR4 topology for synchronous activation of MyD88 and TRIF to orchestrate anti-inflammatory responses in zebrafish

Toll-like receptor 4 (TLR4) plays a critical role in host immunity against Gram-negative bacteria. It transduces signals through two distinct TIR-domain-containing adaptors, MyD88 and TRIF, which function at the plasma membrane and endosomes, respectively. Using zebrafish Aeromonas hydrophila infect...

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Vydáno v:Cell Death Discov
Hlavní autoři: Srivastava, Nidhi, Shelly, Asha, Kumar, Manmohan, Pant, Archana, Das, Bhabatosh, Majumdar, Tanmay, Mazumder, Shibnath
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680545/
https://ncbi.nlm.nih.gov/pubmed/29142761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2017.67
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