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New insight for pharmacogenomics studies from the transcriptional analysis of two large-scale cancer cell line panels

One of the most challenging problems in the development of new anticancer drugs is the very high attrition rate. The so-called “drug repositioning process” propose to find new therapeutic indications to already approved drugs. For this, new analytic methods are required to optimize the information p...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Sadacca, Benjamin, Hamy, Anne-Sophie, Laurent, Cécile, Gestraud, Pierre, Bonsang-Kitzis, Hélène, Pinheiro, Alice, Abecassis, Judith, Neuvial, Pierre, Reyal, Fabien
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680301/
https://ncbi.nlm.nih.gov/pubmed/29123141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14770-6
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