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Phospholipid flippase ATP11C is endocytosed and downregulated following Ca(2+)-mediated protein kinase C activation

We and others showed that ATP11A and ATP11C, members of the P4-ATPase family, translocate phosphatidylserine (PS) and phosphatidylethanolamine from the exoplasmic to the cytoplasmic leaflets at the plasma membrane. PS exposure on the outer leaflet of the plasma membrane in activated platelets, eryth...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Takatsu, Hiroyuki, Takayama, Masahiro, Naito, Tomoki, Takada, Naoto, Tsumagari, Kazuya, Ishihama, Yasushi, Nakayama, Kazuhisa, Shin, Hye-Won
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680300/
https://ncbi.nlm.nih.gov/pubmed/29123098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01338-1
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