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Phospholipid flippase ATP11C is endocytosed and downregulated following Ca(2+)-mediated protein kinase C activation

We and others showed that ATP11A and ATP11C, members of the P4-ATPase family, translocate phosphatidylserine (PS) and phosphatidylethanolamine from the exoplasmic to the cytoplasmic leaflets at the plasma membrane. PS exposure on the outer leaflet of the plasma membrane in activated platelets, eryth...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Takatsu, Hiroyuki, Takayama, Masahiro, Naito, Tomoki, Takada, Naoto, Tsumagari, Kazuya, Ishihama, Yasushi, Nakayama, Kazuhisa, Shin, Hye-Won
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680300/
https://ncbi.nlm.nih.gov/pubmed/29123098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01338-1
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