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A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells

There are presently no reliable ways to quantify endocrine cell mass (ECM) in vivo, which prevents an accurate understanding of the progressive beta cell loss in diabetes or following islet transplantation. To address this unmet need, we coupled RNA sequencing of human pancreatic islets to a systems...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Balhuizen, Alexander, Massa, Sam, Mathijs, Iris, Turatsinze, Jean-Valery, De Vos, Jens, Demine, Stéphane, Xavier, Catarina, Villate, Olatz, Millard, Isabelle, Egrise, Dominique, Capito, Carmen, Scharfmann, Raphaël, In’t Veld, Pieter, Marchetti, Piero, Muyldermans, Serge, Goldman, Serge, Lahoutte, Tony, Bouwens, Luc, Eizirik, Decio L., Devoogdt, Nick
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680294/
https://ncbi.nlm.nih.gov/pubmed/29123178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15417-2
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