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Widespread Expression of a Membrane-Tethered Version of the Soluble Lysosomal Enzyme Palmitoyl Protein Thioesterase-1

“Cross-correction,” the transfer of soluble lysosomal enzymes between neighboring cells, forms the foundation for therapeutics of lysosomal storage disorders (LSDs). However, “cross-correction” poses a significant barrier to studying the role of specific cell types in LSD pathogenesis. By expressing...

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Publicado en:JIMD Rep
Autores principales: Shyng, Charles, Macauley, Shannon L., Dearborn, Joshua T., Sands, Mark S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680291/
https://ncbi.nlm.nih.gov/pubmed/28213849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/8904_2017_1
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