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Histochemical Localization of Palmitoyl Protein Thioesterase-1 Activity

Infantile neuronal ceroid lipofuscinosis (INCL, Infantile Batten disease) is an invariably fatal neurodegenerative pediatric disorder caused by an inherited mutation in the PPT1 gene. Patients with INCL lack the lysosomal enzyme palmitoyl protein thioesterase-1 (PPT1, EC 3.1.2.22), resulting in intr...

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Bibliografiska uppgifter
I publikationen:Mol Genet Metab
Huvudupphovsmän: Dearborn, Joshua T., Ramachandran, Subramania, Shyng, Charles, Lu, Jui-Yun, Thornton, Jonah, Hofmann, Sandra L., Sands, Mark S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755911/
https://ncbi.nlm.nih.gov/pubmed/26597320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2015.11.004
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