DNA methylation at enhancers identifies distinct breast cancer lineages

Breast cancers exhibit genome-wide aberrant DNA methylation patterns. To investigate how these affect the transcriptome and which changes are linked to transformation or progression, we apply genome-wide expression–methylation quantitative trait loci (emQTL) analysis between DNA methylation and gene...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Fleischer, Thomas, Tekpli, Xavier, Mathelier, Anthony, Wang, Shixiong, Nebdal, Daniel, Dhakal, Hari P., Sahlberg, Kristine Kleivi, Schlichting, Ellen, Børresen-Dale, Anne-Lise, Borgen, Elin, Naume, Bjørn, Eskeland, Ragnhild, Frigessi, Arnoldo, Tost, Jörg, Hurtado, Antoni, Kristensen, Vessela N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680222/
https://ncbi.nlm.nih.gov/pubmed/29123100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00510-x
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