Optical Metabolic Imaging Identifies Tumor Cell-Cycle Status on a Single-Cell Level

The goal of this study is to validate fluorescence intensity and lifetime imaging of metabolic co-enzymes NAD(P)H and FAD (optical metabolic imaging, or OMI) as a method to quantify cell-cycle status of tumor cells. Heterogeneity in tumor cell-cycle status (e.g. proliferation, quiescence, apoptosis)...

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Bibliographic Details
Published in:J Biophotonics
Main Authors: Heaster, Tiffany M., Walsh, Alex J., Zhao, Yue, Hiebert, Scott W., Skala, Melissa C.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680147/
https://ncbi.nlm.nih.gov/pubmed/28485124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbio.201600276
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