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Small molecule inhibitors targeting DNA repair and DNA repair deficiency in research and cancer therapy

To maintain stable genomes and to avoid cancer and aging, cells need to repair a multitude of deleterious DNA lesions, which arise constantly in every cell. Processes that support genome integrity in normal cells, however, allow cancer cells to develop resistance to radiation and DNA damaging chemot...

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Podrobná bibliografie
Vydáno v:Cell Chem Biol
Hlavní autoři: Hengel, Sarah R., Spies, M. Ashley, Spies, Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679738/
https://ncbi.nlm.nih.gov/pubmed/28938088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.08.027
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