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Small molecule inhibitors targeting DNA repair and DNA repair deficiency in research and cancer therapy
To maintain stable genomes and to avoid cancer and aging, cells need to repair a multitude of deleterious DNA lesions, which arise constantly in every cell. Processes that support genome integrity in normal cells, however, allow cancer cells to develop resistance to radiation and DNA damaging chemot...
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| Published in: | Cell Chem Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679738/ https://ncbi.nlm.nih.gov/pubmed/28938088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.08.027 |
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