Loading...

Small molecule inhibitors targeting DNA repair and DNA repair deficiency in research and cancer therapy

To maintain stable genomes and to avoid cancer and aging, cells need to repair a multitude of deleterious DNA lesions, which arise constantly in every cell. Processes that support genome integrity in normal cells, however, allow cancer cells to develop resistance to radiation and DNA damaging chemot...

Full description

Saved in:
Bibliographic Details
Published in:Cell Chem Biol
Main Authors: Hengel, Sarah R., Spies, M. Ashley, Spies, Maria
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679738/
https://ncbi.nlm.nih.gov/pubmed/28938088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.08.027
Tags: Add Tag
No Tags, Be the first to tag this record!