Targeting DDX3 with a small molecule inhibitor for lung cancer therapy

Lung cancer is the most common malignancy worldwide and is a focus for developing targeted therapies due to its refractory nature to current treatment. We identified a RNA helicase, DDX3, which is overexpressed in many cancer types including lung cancer and is associated with lower survival in lung...

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發表在:EMBO Mol Med
Main Authors: Bol, Guus M, Vesuna, Farhad, Xie, Min, Zeng, Jing, Aziz, Khaled, Gandhi, Nishant, Levine, Anne, Irving, Ashley, Korz, Dorian, Tantravedi, Saritha, Heerma van Voss, Marise R, Gabrielson, Kathleen, Bordt, Evan A, Polster, Brian M, Cope, Leslie, van der Groep, Petra, Kondaskar, Atul, Rudek, Michelle A, Hosmane, Ramachandra S, van der Wall, Elsken, van Diest, Paul J, Tran, Phuoc T, Raman, Venu
格式: Artigo
語言:Inglês
出版: BlackWell Publishing Ltd 2015
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492822/
https://ncbi.nlm.nih.gov/pubmed/25820276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404368
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