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Loss of Kdm5c causes spurious transcription and prevents the fine-tuning of activity-regulated enhancers in neurons
During development, chromatin-modifying enzymes regulate both the timely establishment of cell type-specific gene programs and the coordinated repression of alternative cell fates. To dissect the role of one such enzyme - the intellectual disability-linked lysine demethylase 5C gene (Kdm5c) – in the...
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| Pubblicato in: | Cell Rep |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679733/ https://ncbi.nlm.nih.gov/pubmed/28978483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.014 |
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