Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages

Clearance of apoptotic cells (ACs) by phagocytes (efferocytosis) prevents post-apoptotic necrosis and dampens inflammation. Defective efferocytosis drives important diseases, including atherosclerosis. For efficient efferocytosis, phagocytes must be able to internalize multiple ACs. We show here tha...

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Udgivet i:Cell
Main Authors: Wang, Ying, Subramanian, Manikandan, Yurdagul, Arif, Barbosa-Lorenzi, Valéria C., Cai, Bishuang, de Juan-Sanz, Jaime, Ryan, Timothy A., Nomura, Masatoshi, Maxfield, Frederick R., Tabas, Ira
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679712/
https://ncbi.nlm.nih.gov/pubmed/28942921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.08.041
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