Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury

Continual efferocytic clearance of apoptotic cells (ACs) by macrophages prevents necrosis and promotes injury resolution. How continual efferocytosis is promoted is not clear. Here, we show that the process is optimized by linking the metabolism of engulfed cargo from initial efferocytic events to s...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Yurdagul, Arif, Subramanian, Manikandan, Wang, Xiaobo, Crown, Scott B., Ilkayeva, Olga, Darville, Lancia, Kolluru, Gopi K., Rymond, Christina C., Gerlach, Brennan D., Zheng, Ze, Kuriakose, George, Kevil, Christopher G., Koomen, John M., Cleveland, John L., Muoio, Deborah M., Tabas, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7173557/
https://ncbi.nlm.nih.gov/pubmed/32004476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.01.001
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