Genetic control of Lyme arthritis by Borrelia burgdorferi arthritis-associated locus 1 (Bbaa1) is dependent on localized differential production of IFN-β and requires upregulation of myostatin

Previously, using a forward genetic approach we identified differential expression of type I IFN as a positional candidate for an expression quantitative trait locus (eQTL) underlying B. burgdorferi arthritis-associated locus 1 (Bbaa1). In this study, we show that mAb blockade revealed a unique role...

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Bibliographic Details
Published in:J Immunol
Main Authors: Paquette, Jackie K., Ma, Ying, Fisher, Colleen, Li, Jinze, Lee, Sang Beum, Zachary, James F., Kim, Yong Soo, Teuscher, Cory, Weis, Janis J.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679706/
https://ncbi.nlm.nih.gov/pubmed/28986440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701011
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