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JARID1 Histone Demethylases: Emerging Targets in Cancer

JARID1 proteins are histone demethylases that both regulate normal cell fates during development and contribute to the epigenetic plasticity that underlies malignant transformation. This H3K4 demethylase family participates in multiple repressive transcriptional complexes at promoters and has broade...

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Veröffentlicht in:Trends Cancer
Hauptverfasser: Harmeyer, Kayla M., Facompre, Nicole D., Herlyn, Meenhard, Basu, Devraj
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679451/
https://ncbi.nlm.nih.gov/pubmed/28958389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2017.08.004
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