Increasing the CpG dinucleotide abundance in the HIV-1 genomic RNA inhibits viral replication

BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) structural protein Gag is necessary and sufficient to form viral particles. In addition to encoding the amino acid sequence for Gag, the underlying RNA sequence could encode cis-acting elements or nucleotide biases that are necessary for vi...

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Bibliografische gegevens
Gepubliceerd in:Retrovirology
Hoofdauteurs: Antzin-Anduetza, Irati, Mahiet, Charlotte, Granger, Luke A., Odendall, Charlotte, Swanson, Chad M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679385/
https://ncbi.nlm.nih.gov/pubmed/29121951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0374-1
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