Detection of circulating miRNAs: comparative analysis of extracellular vesicle-incorporated miRNAs and cell-free miRNAs in whole plasma of prostate cancer patients

BACKGROUND: Circulating cell-free miRNAs have emerged as promising minimally-invasive biomarkers for early detection, prognosis and monitoring of cancer. They can exist in the bloodstream incorporated into extracellular vesicles (EVs) and ribonucleoprotein complexes. However, it is still debated if...

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Vydáno v:BMC Cancer
Hlavní autoři: Endzeliņš, Edgars, Berger, Andreas, Melne, Vita, Bajo-Santos, Cristina, Soboļevska, Kristīne, Ābols, Artūrs, Rodriguez, Marta, Šantare, Daiga, Rudņickiha, Anastasija, Lietuvietis, Vilnis, Llorente, Alicia, Linē, Aija
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679326/
https://ncbi.nlm.nih.gov/pubmed/29121858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3737-z
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