SIDT2 transports extracellular dsRNA into the cytoplasm for innate immune recognition

Double-stranded RNA (dsRNA) is a common by-product of viral infections and acts as a potent trigger of anti-viral immunity. In the nematode C. elegans, sid-1 encodes a dsRNA transporter that is highly conserved throughout animal evolution, but the physiological role of SID-1 and its orthologs remain...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunity
Egile Nagusiak: Nguyen, Tan A., Smith, Blake R. C., Tate, Michelle D, Belz, Gabrielle T., Barrios, Marilou H., Elgass, Kirstin D., Weisman, Alexandra S., Baker, Paul J., Preston, Simon, Whitehead, Lachlan, Garnham, Alexandra, Lundie, Rachel J., Smyth, Gordon K, Pellegrini, Marc, O’Keeffe, Meredith, Wicks, Ian P., Masters, Seth L., Hunter, Craig P., Pang, Ken C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679266/
https://ncbi.nlm.nih.gov/pubmed/28916264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.08.007
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