SIDT2 transports extracellular dsRNA into the cytoplasm for innate immune recognition

Double-stranded RNA (dsRNA) is a common by-product of viral infections and acts as a potent trigger of anti-viral immunity. In the nematode C. elegans, sid-1 encodes a dsRNA transporter that is highly conserved throughout animal evolution, but the physiological role of SID-1 and its orthologs remain...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Nguyen, Tan A., Smith, Blake R. C., Tate, Michelle D, Belz, Gabrielle T., Barrios, Marilou H., Elgass, Kirstin D., Weisman, Alexandra S., Baker, Paul J., Preston, Simon, Whitehead, Lachlan, Garnham, Alexandra, Lundie, Rachel J., Smyth, Gordon K, Pellegrini, Marc, O’Keeffe, Meredith, Wicks, Ian P., Masters, Seth L., Hunter, Craig P., Pang, Ken C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679266/
https://ncbi.nlm.nih.gov/pubmed/28916264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.08.007
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