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Macromolecular assemblies of the mammalian circadian clock
The mammalian circadian clock is built on a feedback loop in which PER and CRY proteins repress their own transcription. We found that in mouse liver nuclei all three PERs, both CRYs, and Casein Kinase-1δ (CK1δ) are present together in a ~1.9-MDa repressor assembly that quantitatively incorporates i...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679067/ https://ncbi.nlm.nih.gov/pubmed/28886335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.07.017 |
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