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Production and Purification of Filovirus Glycoproteins in Insect and Mammalian Cell Lines

Filoviruses are highly virulent pathogens capable of causing severe disease. The glycoproteins of filoviruses are the only virally expressed proteins on the virion surface and are required for receptor binding. As such, they are the main candidate vaccine antigen. Despite their virulence, most filov...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Clarke, Elizabeth C., Collar, Amanda L., Ye, Chunyan, Caì, Yíngyún, Anaya, Eduardo, Rinaldi, Derek, Martinez, Britney, Yarborough, Sarah, Merle, Christine, Theisen, Manfred, Wada, Jiro, Kuhn, Jens H., Bradfute, Steven B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678155/
https://ncbi.nlm.nih.gov/pubmed/29118454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15416-3
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