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Genetic association analysis of microRNA137 and its target complex 1 with schizophrenia in Han Chinese
Recent genome-wide association studies (GWAS) have identified a strong association signal of microRNA137 host gene (MIR137) with schizophrenia. MIR137 dysfunction results in downregulation of presynaptic target gene complexin 1 (CPLX1) and impairs synaptic plasticity in the hippocampus. In this stud...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5678134/ https://ncbi.nlm.nih.gov/pubmed/29118371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15315-7 |
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