Genetic association analysis of microRNA137 and its target complex 1 with schizophrenia in Han Chinese

Recent genome-wide association studies (GWAS) have identified a strong association signal of microRNA137 host gene (MIR137) with schizophrenia. MIR137 dysfunction results in downregulation of presynaptic target gene complexin 1 (CPLX1) and impairs synaptic plasticity in the hippocampus. In this stud...

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Udgivet i:Sci Rep
Main Authors: Lu, Weihong, Zhang, Yi, Fang, Xinyu, Fan, Weixing, Tang, Wei, Cai, Jun, Song, Lisheng, Zhang, Chen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678134/
https://ncbi.nlm.nih.gov/pubmed/29118371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15315-7
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