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The genomic landscape of malignant peripheral nerve sheath tumors: diverse drivers of Ras pathway activation

Malignant peripheral nerve sheath tumor (MPNST) is an aggressive soft tissue sarcoma. To more fully characterize the genomic landscape of this tumor type, we performed next generation sequencing studies for mutational and copy number analysis. We analyzed whole exome sequencing data from 12 MPNST an...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Brohl, Andrew S., Kahen, Elliot, Yoder, Sean J., Teer, Jamie K., Reed, Damon R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678116/
https://ncbi.nlm.nih.gov/pubmed/29118384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15183-1
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