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Isoliquiritigenin Activates Nuclear Factor Erythroid-2 Related Factor 2 to Suppress the NOD-Like Receptor Protein 3 Inflammasome and Inhibits the NF-κB Pathway in Macrophages and in Acute Lung Injury

Among the cellular response mechanisms, the nuclear factor erythroid-2 related factor 2 (Nrf2) pathway is considered a survival pathway that alleviates oxidative injury, while both the NOD-like receptor protein 3 (NLRP3) and NF-κB pathways are pro-inflammatory pathways that cause damage to cells. Th...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Liu, Qinmei, Lv, Hongming, Wen, Zhongmei, Ci, Xinxin, Peng, Liping
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677786/
https://ncbi.nlm.nih.gov/pubmed/29163554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01518
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