Human stem cell-derived retinal epithelial cells activate complement via collectin 11 in response to stress

Age-related macular degeneration (AMD) is a major cause of blindness and is associated with complement dysregulation. The disease is a potential target for stem cell therapy but success is likely to be limited by the inflammatory response. We investigated the innate immune properties of human induce...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Fanelli, Giorgia, Gonzalez-Cordero, Anai, Gardner, Peter J., Peng, Qi, Fernando, Milan, Kloc, Magdalena, Farrar, Conrad A., Naeem, Arifa, Garred, Peter, Ali, Robin R., Sacks, Steven H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677091/
https://ncbi.nlm.nih.gov/pubmed/29116192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15212-z
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