Human stem cell-derived retinal epithelial cells activate complement via collectin 11 in response to stress

Age-related macular degeneration (AMD) is a major cause of blindness and is associated with complement dysregulation. The disease is a potential target for stem cell therapy but success is likely to be limited by the inflammatory response. We investigated the innate immune properties of human induce...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Fanelli, Giorgia, Gonzalez-Cordero, Anai, Gardner, Peter J., Peng, Qi, Fernando, Milan, Kloc, Magdalena, Farrar, Conrad A., Naeem, Arifa, Garred, Peter, Ali, Robin R., Sacks, Steven H.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677091/
https://ncbi.nlm.nih.gov/pubmed/29116192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15212-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items