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Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like (ASPM related primary) microcephaly disease

The development of a cerebral organoid culture in vitro offers an opportunity to generate human brain-like organs to investigate mechanisms of human disease that are specific to the neurogenesis of radial glial (RG) and outer radial glial (oRG) cells in the ventricular zone (VZ) and subventricular z...

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發表在:Protein Cell
Main Authors: Li, Rui, Sun, Le, Fang, Ai, Li, Peng, Wu, Qian, Wang, Xiaoqun
格式: Artigo
語言:Inglês
出版: Higher Education Press 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676597/
https://ncbi.nlm.nih.gov/pubmed/29058117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-017-0479-2
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