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Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like (ASPM related primary) microcephaly disease

The development of a cerebral organoid culture in vitro offers an opportunity to generate human brain-like organs to investigate mechanisms of human disease that are specific to the neurogenesis of radial glial (RG) and outer radial glial (oRG) cells in the ventricular zone (VZ) and subventricular z...

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Pubblicato in:Protein Cell
Autori principali: Li, Rui, Sun, Le, Fang, Ai, Li, Peng, Wu, Qian, Wang, Xiaoqun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Higher Education Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676597/
https://ncbi.nlm.nih.gov/pubmed/29058117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-017-0479-2
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