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Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like (ASPM related primary) microcephaly disease

The development of a cerebral organoid culture in vitro offers an opportunity to generate human brain-like organs to investigate mechanisms of human disease that are specific to the neurogenesis of radial glial (RG) and outer radial glial (oRG) cells in the ventricular zone (VZ) and subventricular z...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Li, Rui, Sun, Le, Fang, Ai, Li, Peng, Wu, Qian, Wang, Xiaoqun
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676597/
https://ncbi.nlm.nih.gov/pubmed/29058117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-017-0479-2
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