DNMT3a contributes to the development and maintenance of bone cancer pain by silencing Kv1.2 expression in spinal cord dorsal horn

Metastatic bone tumor-induced changes in gene transcription and translation in pain-related regions of the nervous system may participate in the development and maintenance of bone cancer pain. Epigenetic modifications including DNA methylation regulate gene transcription. Here, we report that intra...

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Bibliografske podrobnosti
izdano v:Mol Pain
Main Authors: Miao, Xue-Rong, Fan, Long-Chang, Wu, Shaogen, Mao, Qing-Xiang, Li, Zhen, Lutz, Brianna M, Xu, Jitian, Lu, Zhi-Jie, Tao, Yuan-Xiang
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676500/
https://ncbi.nlm.nih.gov/pubmed/29056068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806917740681
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