Contribution of the suppressor of variegation 3–9 homolog 1 in dorsal root ganglia and spinal cord dorsal horn to nerve injury-induced nociceptive hypersensitivity

BACKGROUND: Peripheral nerve injury-induced gene alterations in the dorsal root ganglion (DRG) and spinal cord likely participate in neuropathic pain genesis. Histone methylation gates gene expression. Whether the suppressor of variegation 3–9 homolog 1 (SUV39H1), a histone methyltransferase, contri...

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Publicat a:Anesthesiology
Autors principals: Zhang, Jun, Liang, Lingli, Miao, Xuerong, Wu, Shaogen, Cao, Jing, Tao, Bo, Mao, Qingxiang, Mo, Kai, Xiong, Ming, Lutz, Brianna Marie, Bekker, Alex, Tao, Yuan-Xiang
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030174/
https://ncbi.nlm.nih.gov/pubmed/27483126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000001261
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