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Effective Attenuation of Adenosine A1R Signaling by Neurabin Requires Oligomerization of Neurabin

The adenosine A1 receptor (A1R) is a key mediator of the neuroprotective effect by endogenous adenosine. Yet targeting this receptor for neuroprotection is challenging due to its broad expression throughout the body. A mechanistic understanding of the regulation of A1R signaling is necessary for the...

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Опубликовано в: :Mol Pharmacol
Главные авторы: Chen, Yunjia, Booth, Christopher, Wang, Hongxia, Wang, Raymond X., Terzi, Dimitra, Zachariou, Venetia, Jiao, Kai, Zhang, Jin, Wang, Qin
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676298/
https://ncbi.nlm.nih.gov/pubmed/28954816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.109462
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