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CHD7 interacts with BMP R-SMADs to epigenetically regulate cardiogenesis in mice

Haploinsufficiency for CHD7, an ATP-dependent nucleosome remodeling factor, is the leading cause of CHARGE syndrome. While congenital heart defects (CHDs) are major clinical features of CHARGE syndrome, affecting >75% of patients, it remains unclear whether CHD7 can directly regulate cardiogenic...

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Bibliografische gegevens
Hoofdauteurs: Liu, Yuelong, Harmelink, Cristina, Peng, Yin, Chen, Yunjia, Wang, Qin, Jiao, Kai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959819/
https://ncbi.nlm.nih.gov/pubmed/24293546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt610
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