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CHD7 interacts with BMP R-SMADs to epigenetically regulate cardiogenesis in mice
Haploinsufficiency for CHD7, an ATP-dependent nucleosome remodeling factor, is the leading cause of CHARGE syndrome. While congenital heart defects (CHDs) are major clinical features of CHARGE syndrome, affecting >75% of patients, it remains unclear whether CHD7 can directly regulate cardiogenic...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3959819/ https://ncbi.nlm.nih.gov/pubmed/24293546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt610 |
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