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Will Big Data Close the Missing Heritability Gap?

Despite the important discoveries reported by genome-wide association (GWA) studies, for most traits and diseases the prediction R-squared (R-sq.) achieved with genetic scores remains considerably lower than the trait heritability. Modern biobanks will soon deliver unprecedentedly large biomedical d...

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Detalles Bibliográficos
Publicado en:Genetics
Main Authors: Kim, Hwasoon, Grueneberg, Alexander, Vazquez, Ana I., Hsu, Stephen, de los Campos, Gustavo
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676235/
https://ncbi.nlm.nih.gov/pubmed/28893854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300271
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