Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study

Despite the recent explosive rise in number of genetic markers for complex disease traits identified in genome-wide association studies, there is still a large gap between the known heritability of these traits and the part explained by these markers. To gauge whether this ‘heritability gap’ is clos...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Nolte, Ilja M, van der Most, Peter J, Alizadeh, Behrooz Z, de Bakker, Paul IW, Boezen, H Marike, Bruinenberg, Marcel, Franke, Lude, van der Harst, Pim, Navis, Gerjan, Postma, Dirkje S, Rots, Marianne G, Stolk, Ronald P, Swertz, Morris A, Wolffenbuttel, Bruce HR, Wijmenga, Cisca, Snieder, Harold
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520063/
https://ncbi.nlm.nih.gov/pubmed/28401901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2017.50
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