Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study

Despite the recent explosive rise in number of genetic markers for complex disease traits identified in genome-wide association studies, there is still a large gap between the known heritability of these traits and the part explained by these markers. To gauge whether this ‘heritability gap’ is clos...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Eur J Hum Genet
Prif Awduron: Nolte, Ilja M, van der Most, Peter J, Alizadeh, Behrooz Z, de Bakker, Paul IW, Boezen, H Marike, Bruinenberg, Marcel, Franke, Lude, van der Harst, Pim, Navis, Gerjan, Postma, Dirkje S, Rots, Marianne G, Stolk, Ronald P, Swertz, Morris A, Wolffenbuttel, Bruce HR, Wijmenga, Cisca, Snieder, Harold
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520063/
https://ncbi.nlm.nih.gov/pubmed/28401901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2017.50
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