AB001. Low mitochondrial DNA copy number is associated with low mitochondrial DNA integrity and advanced T-status in non-small cell lung cancer

BACKGROUND: The aim of this study is to appraise the role of mitochondrial DNA (mtDNA) alterations, including the mtDNA copy number and mtDNA integrity (percentage of mtDNA templates without 8-OHdG formation, a marker for oxidative damage to DNA), in non-small cell lung cancer (NSCLC). METHODS: Spec...

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Publicat a:J Thorac Dis
Autors principals: Lin, Chen-Sung, Lee, Ming-Ching, Hsu, Jiin-Chyr, Pan, Siao-Cian, Wei, Yau-Huei
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2017
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676148/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2017.s001
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