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Sirtuins at the crossroads of stemness, aging, and cancer

Sirtuins are stress‐responsive proteins that direct various post‐translational modifications (PTMs) and as a result, are considered to be master regulators of several cellular processes. They are known to both extend lifespan and regulate spontaneous tumor development. As both aging and cancer are a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging Cell
Hauptverfasser: O'Callaghan, Carol, Vassilopoulos, Athanassios
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676072/
https://ncbi.nlm.nih.gov/pubmed/28994177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12685
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