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Sirtuins at the crossroads of stemness, aging, and cancer
Sirtuins are stress‐responsive proteins that direct various post‐translational modifications (PTMs) and as a result, are considered to be master regulators of several cellular processes. They are known to both extend lifespan and regulate spontaneous tumor development. As both aging and cancer are a...
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Publicado no: | Aging Cell |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5676072/ https://ncbi.nlm.nih.gov/pubmed/28994177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12685 |
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