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Sirtuins at the crossroads of stemness, aging, and cancer

Sirtuins are stress‐responsive proteins that direct various post‐translational modifications (PTMs) and as a result, are considered to be master regulators of several cellular processes. They are known to both extend lifespan and regulate spontaneous tumor development. As both aging and cancer are a...

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Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: O'Callaghan, Carol, Vassilopoulos, Athanassios
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676072/
https://ncbi.nlm.nih.gov/pubmed/28994177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12685
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