Hyperphosphatemia induces senescence in human endothelial cells by increasing endothelin‐1 production

Hyperphosphatemia is related to some pathologies, affecting vascular cell behavior. This work analyzes whether high concentration of extracellular phosphate induces endothelial senescence through up‐regulation of endothelin‐1 (ET‐1), exploring the mechanisms involved. The phosphate donor β‐glyceroph...

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Detaylı Bibliyografya
Yayımlandı:Aging Cell
Asıl Yazarlar: Olmos, Gemma, Martínez‐Miguel, Patricia, Alcalde‐Estevez, Elena, Medrano, Diana, Sosa, Patricia, Rodríguez‐Mañas, Leocadio, Naves‐Diaz, Manuel, Rodríguez‐Puyol, Diego, Ruiz‐Torres, María Piedad, López‐Ongil, Susana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676064/
https://ncbi.nlm.nih.gov/pubmed/28857396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12664
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