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Dopamine D4 receptor activation restores CA1 LTP in hippocampal slices from aged mice

Normal aging is characterized with a decline in hippocampal memory functions that is associated with changes in long‐term potentiation (LTP) of the CA3‐to‐CA1 synapse. Age‐related deficit of the dopaminergic system may contribute to impairment of CA1 LTP. Here we assessed how the modulation of CA1 L...

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Bibliografiska uppgifter
I publikationen:Aging Cell
Huvudupphovsmän: Guo, Fangli, Zhao, Jianhua, Zhao, Dandan, Wang, Jiangang, Wang, Xiaofang, Feng, Zhiwei, Vreugdenhil, Martin, Lu, Chengbiao
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676052/
https://ncbi.nlm.nih.gov/pubmed/28975698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12666
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