Dopamine D4 receptor activation restores CA1 LTP in hippocampal slices from aged mice

Normal aging is characterized with a decline in hippocampal memory functions that is associated with changes in long‐term potentiation (LTP) of the CA3‐to‐CA1 synapse. Age‐related deficit of the dopaminergic system may contribute to impairment of CA1 LTP. Here we assessed how the modulation of CA1 L...

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Bibliografske podrobnosti
izdano v:Aging Cell
Main Authors: Guo, Fangli, Zhao, Jianhua, Zhao, Dandan, Wang, Jiangang, Wang, Xiaofang, Feng, Zhiwei, Vreugdenhil, Martin, Lu, Chengbiao
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676052/
https://ncbi.nlm.nih.gov/pubmed/28975698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12666
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