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Dopamine D4 receptor activation restores CA1 LTP in hippocampal slices from aged mice

Normal aging is characterized with a decline in hippocampal memory functions that is associated with changes in long‐term potentiation (LTP) of the CA3‐to‐CA1 synapse. Age‐related deficit of the dopaminergic system may contribute to impairment of CA1 LTP. Here we assessed how the modulation of CA1 L...

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Dettagli Bibliografici
Pubblicato in:Aging Cell
Autori principali: Guo, Fangli, Zhao, Jianhua, Zhao, Dandan, Wang, Jiangang, Wang, Xiaofang, Feng, Zhiwei, Vreugdenhil, Martin, Lu, Chengbiao
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676052/
https://ncbi.nlm.nih.gov/pubmed/28975698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12666
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