DNA vaccination by electroporation amplifies broadly cross-restricted public TCR clonotypes shared with HIV controllers

Rare patients who spontaneously control HIV replication provide a useful model to inform HIV vaccine development. HIV controllers develop particularly efficient antiviral CD4+ T cell responses mediated by shared high-affinity TCRs. To determine whether the candidate DNA vaccine ADVAX could induce si...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Mukhopadhyay, Madhura, Galperin, Moran, Patgaonkar, Mandar, Vasan, Sandhya, Ho, David D., Nouël, Alexandre, Claireaux, Mathieu, Benati, Daniela, Lambotte, Olivier, Huang, Yaoxing, Chakrabarti, Lisa A.
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675813/
https://ncbi.nlm.nih.gov/pubmed/28993513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700953
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