Discovery of stimulation-responsive immune enhancers with CRISPR activation

The majority of genetic variants associated with common human diseases map to enhancers, non-coding elements that shape cell-type-specific transcriptional programs and responses to extracellular cues(1–3). Systematic mapping of functional enhancers and their biological contexts is required to unders...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nature
Main Authors: Simeonov, Dimitre R., Gowen, Benjamin G., Boontanrart, Mandy, Roth, Theodore L., Gagnon, John D., Mumbach, Maxwell R., Satpathy, Ansuman T., Lee, Youjin, Bray, Nicolas L., Chan, Alice Y., Lituiev, Dmytro S., Nguyen, Michelle L., Gate, Rachel E., Subramaniam, Meena, Li, Zhongmei, Woo, Jonathan M., Mitros, Therese, Ray, Graham J., Curie, Gemma L., Naddaf, Nicki, Chu, Julia S., Ma, Hong, Boyer, Eric, Van Gool, Frederic, Huang, Hailiang, Liu, Ruize, Tobin, Victoria R., Schumann, Kathrin, Daly, Mark J., Farh, Kyle K, Ansel, K. Mark, Ye, Chun J., Greenleaf, William J., Anderson, Mark S., Bluestone, Jeffrey A., Chang, Howard Y., Corn, Jacob E., Marson, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675716/
https://ncbi.nlm.nih.gov/pubmed/28854172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23875
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados