Chibby 1: a new component of β-catenin-signaling in chronic myeloid leukemia

Chibby 1 (CBY1) is a small and evolutionarily conserved protein, which act as β-catenin antagonist. CBY1 is encoded by C22orf2 (22q13.1) Its antagonistic function on β-catenin involves the direct interaction with: The C-terminal activation domain of β-catenin, which hinders β-catenin binding with Tc...

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Publicado en:Oncotarget
Autores principales: Mancini, Manuela, Soverini, Simona, Gugliotta, Gabriele, Santucci, Maria Alessandra, Rosti, Gianantonio, Cavo, Michele, Martinelli, Giovanni, Castagnetti, Fausto
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675707/
https://ncbi.nlm.nih.gov/pubmed/29152155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21166
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