BCR-ABL1-Associated Reduction of Beta Catenin Antagonist Chibby1 in Chronic Myeloid Leukemia

Beta Catenin signaling is critical for the self-renewal of leukemic stem cells in chronic myeloid leukemia. It is driven by multiple events, enhancing beta catenin stability and promoting its transcriptional co-activating function. We investigated the impact of BCR-ABL1 on Chibby1, a beta catenin an...

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Autors principals: Leo, Elisa, Mancini, Manuela, Aluigi, Michela, Luatti, Simona, Castagnetti, Fausto, Testoni, Nicoletta, Soverini, Simona, Santucci, Maria Alessandra, Martinelli, Giovanni
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858264/
https://ncbi.nlm.nih.gov/pubmed/24339928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081425
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