Cryptic BCR-ABL fusion gene as variant rearrangement in chronic myeloid leukemia: molecular cytogenetic characterization and influence on TKIs therapy

At diagnosis, about 5% of Chronic Myeloid Leukemia (CML) patients lacks Philadelphia chromosome (Ph), despite the presence of the BCR/ABL rearrangement. Two mechanisms have been proposed about the occurrence of this rearrangement: the first one is a cryptic insertion between chromosomes 9 and 22; th...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Luatti, Simona, Baldazzi, Carmen, Marzocchi, Giulia, Ameli, Gaia, Bochicchio, Maria Teresa, Soverini, Simona, Castagnetti, Fausto, Tiribelli, Mario, Gugliotta, Gabriele, Martinelli, Giovanni, Baccarani, Michele, Cavo, Michele, Rosti, Gianantonio, Testoni, Nicoletta
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444712/
https://ncbi.nlm.nih.gov/pubmed/28404889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15369
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