GFAPδ/GFAPα ratio directs astrocytoma gene expression towards a more malignant profile

Astrocytomas are the most common malignant brain tumours and are to date incurable. It is unclear how astrocytomas progress into higher malignant grades. The intermediate filament cytoskeleton is emerging as an important regulator of malignancy in several tumours. The majority of the astrocytomas ex...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Stassen, Oscar M.J.A., van Bodegraven, Emma J., Giuliani, Fabrizio, Moeton, Martina, Kanski, Regina, Sluijs, Jacqueline A., van Strien, Miriam E., Kamphuis, Willem, Robe, Pierre A.J., Hol, Elly M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675697/
https://ncbi.nlm.nih.gov/pubmed/29152145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21540
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