GFAPδ/GFAPα ratio directs astrocytoma gene expression towards a more malignant profile

Astrocytomas are the most common malignant brain tumours and are to date incurable. It is unclear how astrocytomas progress into higher malignant grades. The intermediate filament cytoskeleton is emerging as an important regulator of malignancy in several tumours. The majority of the astrocytomas ex...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Stassen, Oscar M.J.A., van Bodegraven, Emma J., Giuliani, Fabrizio, Moeton, Martina, Kanski, Regina, Sluijs, Jacqueline A., van Strien, Miriam E., Kamphuis, Willem, Robe, Pierre A.J., Hol, Elly M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675697/
https://ncbi.nlm.nih.gov/pubmed/29152145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21540
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