Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytoma

To identify cellular and molecular changes that driver pediatric low grade glioma (PLGG) progression, we analyzed putative cancer stem cells (CSCs) and evaluated key biological changes in a novel and progressive patient-derived orthotopic xenograft (PDOX) mouse model. Flow cytometric analysis of 22...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kogiso, Mari, Qi, Lin, Lindsay, Holly, Huang, Yulun, Zhao, Xiumei, Liu, Zhigang, Braun, Frank K., Du, Yuchen, Zhang, Huiyuan, Bae, Goeun, Zhao, Sibo, Injac, Sarah G., Sobieski, Mary, Brunell, David, Mehta, Vidya, Tran, Diep, Murray, Jeffrey, Baxter, Patricia A., Yuan, Xiao-Jun, Su, Jack M., Adesina, Adekunle, Perlaky, Laszlo, Chintagumpala, Murali, Parsons, D. Williams, Lau, Ching C., Stephan, Clifford C., Lu, Xinyan, Li, Xiao-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675646/
https://ncbi.nlm.nih.gov/pubmed/29152094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20713
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados